Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances Export

@article{citeulike:1142301, abstract = {Perceiving a pharmacophore is the first essential step towards understanding the interaction between a receptor and a ligand. Once a pharmacophore is established, a beneficial use of it is 3D database searching to retrieve novel compounds that would match the pharmacophore. As the 3D searching technology has evolved over the years, it has been effectively used for lead optimization, combinatorial library focusing, as well as virtual high-throughput screening. This paper is an update to the original paper published in this journal earlier: Kurogi, Y, and G\üner, O. F. \&\#147;Pharmacophore Modeling and Three-Dimensional Database Searching for Drug Design Using Catalyst,\&\#148; in Current Medicinal Chemistry, 2001, 8(9), 1035-1055.}, author = {Guner, Osman}, citeulike-article-id = {1142301}, citeulike-linkout-0 = {http://www.ingentaconnect.com/content/ben/cmc/2004/00000011/00000022/art00003}, keywords = {library, screening}, month = {November}, pages = {2991--3005}, posted-at = {2007-03-05 21:16:33}, priority = {2}, title = {Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances}, url = {http://www.ingentaconnect.com/content/ben/cmc/2004/00000011/00000022/art00003} }

TY - JOUR ID - citeulike:1142301 L3 - citeulike-article-id:1142301 N2 - Perceiving a pharmacophore is the first essential step towards understanding the interaction between a receptor and a ligand. Once a pharmacophore is established, a beneficial use of it is 3D database searching to retrieve novel compounds that would match the pharmacophore. As the 3D searching technology has evolved over the years, it has been effectively used for lead optimization, combinatorial library focusing, as well as virtual high-throughput screening. This paper is an update to the original paper published in this journal earlier: Kurogi, Y, and Güner, O. F. “Pharmacophore Modeling and Three-Dimensional Database Searching for Drug Design Using Catalyst,” in Current Medicinal Chemistry, 2001, 8(9), 1035-1055. EP - 3005 TI - Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances SP - 2991 KW - library KW - screening AU - Guner, Osman UR - http://www.ingentaconnect.com/content/ben/cmc/2004/00000011/00000022/art00003 ER -