Optical studies of single molecules at room temperature.

@article{citeulike:2632596, abstract = {Recent developments in optical studies of single molecules at room temperature are reviewed, with an emphasis on the underlying principles and the potential of single-molecule experiments. Examples of single-molecule studies are given, including photophysics and photochemistry pertinent to single-molecule measurements, spectral fluctuations, Raman spectroscopy, diffusional motions, conformational dynamics, fluorescence resonant energy transfer, exciton dynamics, and enzymatic turnovers. These studies illustrate the information obtainable with the single-molecule approach that is hidden in ensemble-averaged measurements.}, address = {Pacific Northwest National Laboratory, Environmental Molecular Sciences Laboratory, PO Box 999, K8-88, Richland, Washington 99352, USA. xsxie@pnl.gov}, author = {Xie, X. S. and Trautman, J. K. }, citeulike-article-id = {2632596}, doi = {10.1146/annurev.physchem.49.1.441}, issn = {0066-426X}, journal = {Annual review of physical chemistry}, keywords = {classic, single\_molecule}, pages = {441--480}, posted-at = {2008-04-05 15:11:28}, priority = {2}, title = {Optical studies of single molecules at room temperature.}, url = {http://dx.doi.org/10.1146/annurev.physchem.49.1.441}, volume = {49}, year = {1998} }

TY - JOUR ID - citeulike:2632596 L3 - citeulike-article-id:2632596 TI - Optical studies of single molecules at room temperature. JF - Annual review of physical chemistry VL - 49 SP - 441 EP - 480 AD - Pacific Northwest National Laboratory, Environmental Molecular Sciences Laboratory, PO Box 999, K8-88, Richland, Washington 99352, USA. xsxie@pnl.gov SN - 0066-426X N2 - Recent developments in optical studies of single molecules at room temperature are reviewed, with an emphasis on the underlying principles and the potential of single-molecule experiments. Examples of single-molecule studies are given, including photophysics and photochemistry pertinent to single-molecule measurements, spectral fluctuations, Raman spectroscopy, diffusional motions, conformational dynamics, fluorescence resonant energy transfer, exciton dynamics, and enzymatic turnovers. These studies illustrate the information obtainable with the single-molecule approach that is hidden in ensemble-averaged measurements. KW - classic KW - single_molecule AU - Xie, XS AU - Trautman, JK PY - 1998/// UR - http://dx.doi.org/10.1146/annurev.physchem.49.1.441 ER -