STAMP: a web tool for exploring DNA-binding motif similarities Export

@article{citeulike:1320157, abstract = {STAMP is a newly developed web server that is designed to support the study of DNA-binding motifs. STAMP may be used to query motifs against databases of known motifs; the software aligns input motifs against the chosen database (or alternatively against a user-provided dataset), and lists of the highest-scoring matches are returned. Such similarity-search functionality is expected to facilitate the identification of transcription factors that potentially interact with newly discovered motifs. STAMP also automatically builds multiple alignments, familial binding profiles and similarity trees when more than one motif is inputted. These functions are expected to enable evolutionary studies on sets of related motifs and fixed-order regulatory modules, as well as illustrating similarities and redundancies within the input motif collection. STAMP is a highly flexible alignment platform, allowing users to mix-and-match' between various implemented comparison metrics, alignment methods (local or global, gapped or ungapped), multiple alignment strategies and tree-building methods. Motifs may be inputted as frequency matrices (in many of the commonly used formats), consensus sequences, or alignments of known binding sites. STAMP also directly accepts the output files from 12 supported motif-finders, enabling quick interpretation of motif-discovery analyses. STAMP is available at http://www.benoslab.pitt.edu/stamp 10.1093/nar/gkm272}, address = {Department of Computational Biology, School of Medicine, University of Pittsburgh and Department of Human Genetics, Graduate School of Public Health, and University of Pittsburgh Cancer Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.}, author = {Mahony, Shaun and Benos, Panayiotis V.}, booktitle = {Nucl. Acids Res.}, citeulike-article-id = {1320157}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/nar/gkm272}, citeulike-linkout-1 = {http://nar.oxfordjournals.org/cgi/content/abstract/35/suppl_2/W253}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17478497}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17478497}, day = {13}, doi = {10.1093/nar/gkm272}, issn = {1362-4962}, journal = {Nucleic acids research}, keywords = {stamp}, month = {July}, number = {suppl\_2}, pages = {W253--258}, posted-at = {2009-08-13 04:24:20}, priority = {2}, title = {STAMP: a web tool for exploring DNA-binding motif similarities}, url = {http://dx.doi.org/10.1093/nar/gkm272}, volume = {35}, year = {2007} }

TY - JOUR ID - citeulike:1320157 L3 - citeulike-article-id:1320157 N2 - STAMP is a newly developed web server that is designed to support the study of DNA-binding motifs. STAMP may be used to query motifs against databases of known motifs; the software aligns input motifs against the chosen database (or alternatively against a user-provided dataset), and lists of the highest-scoring matches are returned. Such similarity-search functionality is expected to facilitate the identification of transcription factors that potentially interact with newly discovered motifs. STAMP also automatically builds multiple alignments, familial binding profiles and similarity trees when more than one motif is inputted. These functions are expected to enable evolutionary studies on sets of related motifs and fixed-order regulatory modules, as well as illustrating similarities and redundancies within the input motif collection. STAMP is a highly flexible alignment platform, allowing users to mix-and-match' between various implemented comparison metrics, alignment methods (local or global, gapped or ungapped), multiple alignment strategies and tree-building methods. Motifs may be inputted as frequency matrices (in many of the commonly used formats), consensus sequences, or alignments of known binding sites. STAMP also directly accepts the output files from 12 supported motif-finders, enabling quick interpretation of motif-discovery analyses. STAMP is available at http://www.benoslab.pitt.edu/stamp 10.1093/nar/gkm272 IS - suppl_2 JF - Nucleic acids research SN - 1362-4962 AD - Department of Computational Biology, School of Medicine, University of Pittsburgh and Department of Human Genetics, Graduate School of Public Health, and University of Pittsburgh Cancer Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA. EP - 258 TI - STAMP: a web tool for exploring DNA-binding motif similarities VL - 35 T2 - Nucl. Acids Res. SP - W253 KW - stamp AU - Mahony, Shaun AU - Benos, Panayiotis PY - 2007/07/13/ UR - http://dx.doi.org/10.1093/nar/gkm272 ER -