Phenotypic Diversity, Population Growth, and Information in Fluctuating Environments Export

@article{kussell2005pdp, abstract = {Organisms in fluctuating environments must constantly adapt their behavior to survive. In clonal populations, this may be achieved through sensing followed by response or through the generation of diversity by stochastic phenotype switching. Here we show that stochastic switching can be favored over sensing when the environment changes infrequently. The optimal switching rates then mimic the statistics of environmental changes. We derive a relation between the long-term growth rate of the organism and the information available about its fluctuating environment. 10.1126/science.1114383}, address = {Laboratory of Living Matter and Center for Studies in Physics and Biology, The Rockefeller University, 1230 York Avenue, Box 34, New York, NY 10021-6399, USA.}, author = {Kussell, Edo and Leibler, Stanislas}, citeulike-article-id = {331510}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1114383}, citeulike-linkout-1 = {http://www.sciencemag.org/content/309/5743/2075.abstract}, citeulike-linkout-2 = {http://www.sciencemag.org/content/309/5743/2075.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/16123265}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=16123265}, citeulike-linkout-5 = {http://www.sciencemag.org/cgi/content/full/309/5743/2075}, day = {23}, doi = {10.1126/science.1114383}, issn = {1095-9203}, journal = {Science}, keywords = {diversity, fitness, information, population}, month = {September}, number = {5743}, pages = {2075--2078}, posted-at = {2008-05-26 10:37:08}, priority = {0}, title = {Phenotypic Diversity, Population Growth, and Information in Fluctuating Environments}, url = {http://dx.doi.org/10.1126/science.1114383}, volume = {309}, year = {2005} }

TY - JOUR ID - kussell2005pdp L3 - citeulike-article-id:331510 N2 - Organisms in fluctuating environments must constantly adapt their behavior to survive. In clonal populations, this may be achieved through sensing followed by response or through the generation of diversity by stochastic phenotype switching. Here we show that stochastic switching can be favored over sensing when the environment changes infrequently. The optimal switching rates then mimic the statistics of environmental changes. We derive a relation between the long-term growth rate of the organism and the information available about its fluctuating environment. 10.1126/science.1114383 IS - 5743 JF - Science SN - 1095-9203 AD - Laboratory of Living Matter and Center for Studies in Physics and Biology, The Rockefeller University, 1230 York Avenue, Box 34, New York, NY 10021-6399, USA. EP - 2078 TI - Phenotypic Diversity, Population Growth, and Information in Fluctuating Environments VL - 309 SP - 2075 KW - diversity KW - fitness KW - information KW - population AU - Kussell, Edo AU - Leibler, Stanislas PY - 2005/09/23/ UR - http://dx.doi.org/10.1126/science.1114383 ER -