Mapping Adverse Drug Reactions in Chemical Space Export

@article{ScheiberJS09, abstract = {We present a novel method to better investigate adverse drug reactions in chemical space. By integrating data sources about adverse drug reactions of drugs with an established cheminformatics modeling method, we generate a data set that is then visualized with a systems biology tool. Thereby new insights into undesired drug effects are gained. In this work, we present a global analysis linking chemical features to adverse drug reactions.}, author = {Scheiber, Josef and Jenkins, Jeremy L. and Sukuru, Sai C. and Bender, Andreas and Mikhailov, Dmitri and Milik, Mariusz and Azzaoui, Kamal and Whitebread, Steven and Hamon, Jacques and Urban, Laszlo and Glick, Meir and Davies, John W.}, citeulike-article-id = {4373192}, citeulike-linkout-0 = {http://dx.doi.org/10.1021/jm801546k}, citeulike-linkout-1 = {http://pubs.acs.org/doi/abs/10.1021/jm801546k}, day = {14}, doi = {10.1021/jm801546k}, journal = {Journal of Medicinal Chemistry}, keywords = {adverse, biology, chemical, drug, reactions, space, systems}, month = {May}, number = {9}, pages = {3103--3107}, posted-at = {2009-06-26 15:28:33}, priority = {2}, title = {Mapping Adverse Drug Reactions in Chemical Space}, url = {http://dx.doi.org/10.1021/jm801546k}, volume = {52}, year = {2009} }

TY - JOUR ID - ScheiberJS09 L3 - citeulike-article-id:4373192 N2 - We present a novel method to better investigate adverse drug reactions in chemical space. By integrating data sources about adverse drug reactions of drugs with an established cheminformatics modeling method, we generate a data set that is then visualized with a systems biology tool. Thereby new insights into undesired drug effects are gained. In this work, we present a global analysis linking chemical features to adverse drug reactions. IS - 9 JF - Journal of Medicinal Chemistry EP - 3107 TI - Mapping Adverse Drug Reactions in Chemical Space VL - 52 SP - 3103 KW - adverse KW - biology KW - chemical KW - drug KW - reactions KW - space KW - systems AU - Scheiber, Josef AU - Jenkins, Jeremy AU - Sukuru, Sai AU - Bender, Andreas AU - Mikhailov, Dmitri AU - Milik, Mariusz AU - Azzaoui, Kamal AU - Whitebread, Steven AU - Hamon, Jacques AU - Urban, Laszlo AU - Glick, Meir AU - Davies, John PY - 2009/05/14/ UR - http://dx.doi.org/10.1021/jm801546k ER -