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Mutation analysis of microRNA-7 gene in Chinese patients with Parkinson's disease.

by: Xuewei Zhang, Jifeng Guo, Sanxi Ai, Yaceng Hu, Qiying Sun, Qian Xu, Zhanyun Lu, Kai Li, Xiaoli Dong, Lu Shen, Hong Jiang, Qian Pan, Kun Xia, Xinxiang Yan, Beisha Tang
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, Vol. 37, No. 12. (December 2012), pp. 1189-1192, doi:10.3969/j.issn.1672-7347.2012.12.001  Key: citeulike:11865145

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Abstract

Objective: To investigate the mutation of small sequence changes in microRNA-7 gene in Chinese patients with Parkinson's disease (PD). Methods: We analyzed miR-7 variants in 225 PD patients from Chinese Han group by DNA sequence. Results: None of the patients had miR-7 variants. Conclusion: MiR-7 variation is not associated with PD in Chinese patients.


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